PERSICARIA MINOR (HUDS.) OPIZ EXHIBITS ANTIHYPERTENSIVE EFFECTS BY INHIBITING THE ANGIOTENSIN-CONVERTING ENZYME/ANGIOTENSIN II TYPE 1 RECEPTOR PATHWAY IN HUMAN ENDOTHELIAL CELLS

Overactivation of the angiotensin-converting Hats enzyme (ACE)/angiotensin II type 1 receptor (AT1R) pathway leads to vasoconstriction and elevated blood pressure.Persicaria minor (Huds.) Opiz is an herbal plant known for its antioxidant, anti-hyperlipidemic, and anti-atherosclerotic properties, with bioactive compounds that exhibit antihypertensiv

Elevated proinflammatory cytokines were reported in binge eating spectrum disorders characterized by intermittent overconsumption during periods of otherwise normal or restricted food intake.It is unknown whether binge eating promotes neuroinflammation, similar to that observed following chronic overconsumption of a Mattress Protectors high fat die

The primary goal of this study is to introduce the initial phase of developing an impact-based forecasting system for extreme heatwaves, utilizing a novel multivariate index which, at this early stage, already employs a combination of a statistical approach and physical principles related to human body water loss.This system also incorporates a mit

Summary: Response to threatening environmental stimuli requires detection and encoding of important environmental features that dictate threat.Aversive events are highly salient, which promotes associative learning about stimuli that blanke signal this threat.The nucleus accumbens is uniquely positioned to process this salient, aversive information